Dentinogenesis is the formation of dentin, a substance that forms the majority of teeth. Dentinogenesis is performed by odontoblasts, which are a special type of biological cell on the outer wall of dental pulps, and it begins at the late bell stage of a tooth development. Odontoblasts differentiate from cells of the dental papilla. This is an expression of signaling molecules and growth factors of the inner enamel epithelium.

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